ABSTRACT This study aimed to characterize the occurrence, duration, and intensity of the flushes of vegetative growth in two peach cultivars of Prunus persica L. Batsch, grown as a pioneer endeavor at a high-altitude tropical climate site in the State of Minas Gerais, Brazil. The observational experiment was carried out in 2017/18 and 2018/19 on the ‘Tropic Beauty’ and ‘BRS Kampai’ cultivars by an evaluation of the number and duration of flushes of vegetative growth during the year over two cycles. The number of fruit-bearing shoots, total number of leaves and shoot length were also assessed. At harvest, fruit load and diameter were determined and grouped into diameter ranges. The number of hours recorded at different temperature ranges, < 10.0 °C; 10.1-15.0 °C; 15.1-20.0 °C; 20.1-25.0 °C; > 25.1 °C, were summed separately and divided into daily and nightly periods. The peach tree has an unusual vegetative growth pattern when cultivated in a tropical area, which occurs in two flushes, with the first flush occurring from budbreak to fruit harvest between June and Sept, forming short shoots (less than 10 cm), with early shoot growth cessation, with a limited leaf number that can potentially diminish the supply of carbohydrates to the fruit, leading to smaller growth. The second flush occurs after harvest, between Oct and Dec, when there is an increase in daily temperature and precipitation, and no competition with fruits. Notabily, these second flush shoots grow with greater vigor and regularization of the growth cycle, forming fruit-bearing shoots with abundant leaf and flower buds for the next production cycle.

ABSTRACT Background: Polypectomy is an important treatment option for preventing colorectal cancer. Incomplete polyp resection (IPR) is recognized as a risk factor for interval cancer. Objective: The primary objective was to evaluate the complete polyp resection (CPR) rate for cold snare polypectomy (CSP) in small non-pedunculated polyps and, secondarily, specimen retrieval and complication rates. Methods: We prospectively evaluated 479 polyps <10 mm removed by CSP in 276 patients by an inexperienced endoscopist. Results: A total of 476 polyps (99.4%) were resected en bloc. A negative margin (classified as CPR) was observed in 435 polyps (90.8%). An unclear or positive margin (classified as IPR) was observed in 43 cases (9.0%) and 1 case (0.2%), respectively, for an overall IPR rate of 9.2% (44/479). The IPR rate was 12.2% in the first half of cases and 5.9% in the second half (P=0.02). Dividing into tertiles, the IPR rate was 15.0% in the first tertile, 6.9% in the second tertile, and 5.7% in the third tertile (P=0.01). Dividing into quartiles, the IPR rate was 15.8% in the first quartile and 5.9% in the fourth quartile (P=0.03). The IPR rate was 6.3% for type 0-IIa lesions and 14.1% for type 0-Is lesions (P=0.01). For serrated and adenomatous lesions, the IPR rate was 9.2%. Specimen retrieval failed in 3.6% of cases. Immediate bleeding (>30 s) occurred in 1 case (0.2%), treated with argon plasma coagulation. No delayed bleeding or perforation occurred. Conclusion: CSP is a safe technique that provides good results for the resection of small non-pedunculated polyps, with a short learning curve.

RESUMO Contexto: A polipectomia é uma importante opção terapêutica na prevenção do câncer colorretal (CCR). A ressecção incompleta do pólipo (RIP) é reconhecida como fator de risco para o câncer de intervalo. Objetivo: O principal objetivo foi avaliar o índice de ressecção completa da polipectomia a frio (PF) em pequenos pólipos não pediculados e, secundariamente, a recuperação do espécime e índice de complicações. Métodos: Avaliamos prospectivamente 479 pólipos <10 mm removidos por PF em 276 pacientes, por um endoscopista sem experiência com este método. Resultados: Foram ressecados em bloco 476 pólipos (99,4%). Tivemos margem negativa, considerada ressecção completa do pólipo (RCP), em 435 (90,8%) casos. Margem indefinida ou positiva (classificada como RIP) foi observada em 43 (9,0%) casos e em 1 (0,2%) caso, respectivamente, com um índice global de RIP de 9,2% (44/479). O índice de RIP foi de 12,5% na primeira metade dos casos e 5,9% na última metade (P=0,02). Dividindo em tercis, o índice de RIP foi de 15,0% no primeiro terço, 6,9% no segundo terço e 5,7% no terceiro quarto, P=0,01. Dividindo em quartis, o índice de RIP foi de 15,8% no primeiro quarto, enquanto o último quarto foi de 5,9%, P=0,03. O índice de RIP foi de 6,3% para lesões tipo 0-IIa e de 14,1% para lesões tipo 0-Is, P=0,01. O índice de RIP foi de 9,2% para lesões serrilhadas e adenomatosas. Houve falha na recuperação dos espécimes em 3,6% dos casos. Sangramento imediato (>30 s) ocorreu em um caso (0,2%), controlado com plasma de argônio. Sem sangramento tardio e perfuração. Conclusão: PF é uma técnica segura que apresenta bons resultados para a ressecção de pequenas lesões não pediculadas, com uma curta curva aprendizado.

Introduction: Improved endoscopic imaging allows the differential diagnosis of colorectal lesions in real time through the study of the microvasculature. Objective: To review the use of Blue Laser Imaging (BLI) in analyzing the capillary patern for the differential diagnosis between neoplastic and non-neoplastic lesions. Method: This is an integrative review of the literature that collected information published on virtual platforms in Portuguese and English. The search for reading and analysis was carried out on the SciELO – Scientific Electronic Library Online, Google Scholar, Pubmed and Scopus platforms. The descriptors taken from DeCS/MESH were: “Blue laser imaging. Endoscopy. Chromoendoscopy, Colorectal polyps. Magnification” and its English counterparts “Blue laser imaging. Image-enhanced endoscopy. Chromoendoscopy. Colorectal polyps. Magnification” with AND or OR search, considering the title and/or abstract. Only those that had the greatest correlation to the topic were included, and the review was based on them, with reading, in full, of the texts. Results: In the end, 22 articles resulted that made up this review. Conclusion: BLI associated with magnification showed good results in real-time predictive histological diagnosis for colon and rectal lesions.

Introdução: Imagem endoscópica aprimorada permite o diagnóstico diferencial das lesões colorretais em tempo real através do estudo da microvasculatura. Objetivo: Revisar o uso do Blue Laser Imaging (BLI) na análise do padrão dos capilares para o diagnóstico diferencial entre lesões neoplásicas e não neoplásicas. Método: Esta é revisão integrativa da literatura&nbsp; que colheu informações publicadas em plataformas virtuais em português e inglês. A busca para leitura e análise foi realizada nas plataformas SciELO – Scientific Electronic Library Online, Google Scholar, Pubmed e Scopus. &nbsp;Os descritores retirados do DeCS/MESH foram: “Blue laser imaging. Endoscopia. Cromoendoscopia, Pólipos colorretais. Magnificação” e seus correspondentes em inglês “Blue laser imaging. Image-enhanced endoscopy. Chromoendoscopy. Colorectal polyps. Magnification” com busca AND ou OR, considerando o título e/ou resumo. Foram incluídos somente os que tivessem maior correlação ao tema, e neles foi baseada a revisão com leitura, na íntegra, dos textos. Resultados: Ao final resultaram &nbsp;22 artigos que compuseram esta revisão. Conclusão: BLI associada à magnificação mostrou bons resultados no diagnóstico histológico preditivo em tempo real para as lesões de cólon e reto.

This article discusses one of the possibilities for changes in the teaching and learning process of geometric thinking in the face of the exponential appropriation of digital technology. The objective of the research was to develop activities focused on students of the first period of the Architecture and Urbanism course, using the Minecraft game. The article is the result of both bibliographical and empirical research, of a didactic experience. Through a practical application at the Juiz de Fora Federal University, it was pointed out that the use of games can contribute to the development of spatial skills and geometric thinking of students in the first periods of the Architecture and Urbanism course. In a simulated three-dimensional environment of a digital game, students are encouraged to use geometric reasoning for the composition of architectures, associating space with forms and rationalizing the architectural compositional process.

Este artículo discute una de las posibilidades de cambios en el proceso de enseñanza y aprendizaje del pensamiento geométrico frente a la apropiación exponencial de la tecnología digital. El objetivo de la investigación fue desarrollar actividades enfocadas a los estudiantes del primer período de la carrera de Arquitectura y Urbanismo, utilizando el juego Minecraft. El artículo es el resultado de una investigación tanto bibliográfica como empírica, de una experiencia didáctica. A través de una aplicación práctica en la Universidad Federal Juiz de Fora, se señaló que el uso de juegos puede contribuir al desarrollo de las habilidades espaciales y el pensamiento geométrico de los estudiantes de los primeros períodos de la carrera de Arquitectura y Urbanismo. En un entorno tridimensional simulado de un juego digital, se anima a los estudiantes a utilizar el razonamiento geométrico para la composición de arquitecturas, asociando el espacio con las formas y racionalizando el proceso compositivo arquitectónico.

Este artigo discute uma das possibilidades de mudanças no processo de ensino e aprendizado do pensamento geométrico face à apropriação exponencial da tecnologia digital. O objetivo da pesquisa foi desenvolver atividades focadas em discentes de primeiro período do curso de Arquitetura e Urbanismo, utilizando o jogo Minecraft. O artigo é resultado de uma pesquisa tanto bibliográfica quanto empírica, de uma experiência didática. Por meio de uma aplicação prática na Universidade Federal de Juiz de Fora, apontou-se que o uso dos jogos pode contribuir para o desenvolvimento das habilidades espaciais e o pensamento geométrico dos estudantes dos primeiros períodos do curso de Arquitetura e Urbanismo. Em um ambiente tridimensional simulado de jogo digital, os discentes são estimulados a utilizarem raciocínio geométrico para a composição de arquiteturas, associando o espaço às formas e racionalizando o processo compositivo arquitetônico.

ABSTRACT The aim of this study was to evaluate the genotypes developed by the Peach Breeding Program at the Federal University of Viçosa, as regards to resistance to M. incognita. Six rootstocks genotypes propagated by cuttings (713-07, 713-13, 913-3, 913-6, 913-11 and 913-17) and two rootstocks propagated by seeds (‘Okinawa’ and hybrid between scion cultivars Aurora 2 x Aurora 1), were evaluated. The experimental design was randomized block design with five replicates and one plant per experimental units. After establishing the plants in pot, maintained in a greenhouse, this were inoculated with 11.000 juveniles + eggs of M. incognita. Evaluations were performed at 140 days after inoculation. The roots were evaluated and the number of galls and egg mass in the roots were determined. The eggs were extracted from each plant for quantification and determination of the Reproduction Factor (RF) of the nematode. The peach genotypes 913-3, 913-6, 913-11, 913-17 and 713-7 showed an immune reaction to M. incognita. Genotype 713-13 showed susceptible reaction to M. incognita. The hybrid between scion cultivars Aurora 2 x Aurora 1 confirmed susceptible.

RESUMO Contexto Ressecção endoscópica da mucosa (REM) é uma opção fácil para o tratamento das lesões superficiais do cólon e reto, inclusive para as lesões ≥20 mm de diâmetro. Objetivo Avaliar a efetividade da REM. Métodos Este estudo prospectivo observacional avaliou 430 lesões ressecadas por REM em 404 pacientes. As lesões foram analisadas de acordo com a morfologia, tamanho, localização e histologia. Lesões <20 mm foram removidas em bloco, enquanto lesões ≥20 mm foram ressecadas em piecemeal REM (p-REM). Eventos adversos e recorrência foram avaliados. Resultados Quanto à morfologia, 145 (33,7%) eram lesões deprimidas, 157 (36,5%) eram lesões polipoides e 128 (29,8%) eram lesões que se espalham lateralmente, com 361 (84%) lesões <20 mm e 69 (16%) ≥20 mm. Em relação à histologia, 413 (96%) foram classificadas como lesões neoplásicas. Globalmente tivemos 14 (3,3%) de reações adversas, mais presente nas lesões ≥20 mm removidas por p-REM (P<0,001) e associadas com histologia avançada (P=0,008). A recorrência ocorreu em 14 (5,2%) casos, sendo mais observada em lesões removidas por p-REM (P<0,001). Conclusão REM é uma técnica efetiva para o tratamento das lesões colorretais superficiais, até mesmo para as grandes lesões.

ABSTRACT Background Endoscopic mucosal resection (EMR) is an easy-to-use treatment option for superficial colorectal lesions, including lesions ≥20 mm. Objective To evaluate the effectiveness of EMR. Methods We evaluated 430 lesions removed by EMR in 404 patients. The lesions were analyzed according to their morphology, size, location, and histology. Lesions <20 mm were resected en bloc, whereas lesions ≥20 mm were removed by piecemeal EMR (p-EMR). Adverse events and recurrence were assessed. Results Regarding morphology, 145 (33.7%) were depressed lesions, 157 (36.5%) were polypoid lesions and 128 (29.8%) were laterally spreading lesions, with 361 (84%) lesions <20 mm and 69 (16%) ≥20 mm. Regarding histology, 413 (96%) lesions were classified as neoplastic lesions. Overall, 14 (3.3%) adverse reactions occurred, most commonly in lesions removed by p-EMR (P<0.001) and associated with advanced histology (P=0.008). Recurrence occurred in 14 (5.2%) cases, more commonly in lesions removed by p-EMR (P<0.001). Conclusion EMR is an effective technique for the treatment of superficial colorectal lesions, even of large lesions.

Abstract The present study aimed to evaluate the storage fruit potential of sour passion fruit progenies at temperatures of 7, 14 and 25 °C. The fruits were harvested at 30% yellow peel color, selected, sanitized and stored under refrigeration in chambers with relative humidity of 80% (± 5%) for a period of 12 days. The experiment was installed in a factorial scheme (3 × 3 × 4), with three progenies selected in the breeding program (P42, P45 and P49), three storage temperatures (7, 14 and 25 ° C) and four evaluation periods (0, 4, 8 and 12 days after storage). Analyzes of fruit mass, pulp mass, pericarp mass, pulp yield, pericarp thickness, water loss, soluble solids content, titratable acidity and ascorbic acid content were performed. There were significant differences among the studied progenies, P49 showed better traits than the other progenies, mainly regarding the resistance to water loss, the main trait that affects the quality of the fruits. Storage at 14 °C for twelve days is feasible to maintain the quality of sour passion fruit. The temperature of 7 °C inhibits the ripening of the fruits and promotes dehydration, confirming the non-recommendation of storage in this condition.

Abstract Objective was evaluated the therapeutic effect of Juglans regia (J) and Zingiber officinale (Z) extracts, alone or associated (Z75% + J25%, Z50% + J50% and Z25% + J75%) applied on planktonic cultures and biofilms of Propionibacterium acnes, Staphylococcus epidermidis and Staphylococcus aureus, as well as analyzing the cytotoxic effects of plant extracts on mouse macrophages (Raw 264-7). Broth microdilution assay was performed (M7-A6 - CLSI). Anti-biofilm activities and cytotoxicity on Raw 264-7 were studied using MTT assay and scanning electron microscopy. ANOVA with post-hoc Tukey HSD applied for parametric data and Kruskal-Wallis with Conover-Iman test, for non-parametric (p<0.05). On P. acnes biofilm, Z50% + J50% reduced 46.9% in 5 min and Z25% + J75% reduced 74.1% in 24hs. On S. aureus, Z75% + J25% reduced 23.1% in 5 min Z25% +J75% reduced 79.4% in 24hs. On S. epidermidis, Z75% + J25% reduced 74.6% in 5 min and 82.05% in 24 h. The treatments on macrophages for 24 h promoted a maximum reduction by 14,5% for groups of extracts associations. On multispecies biofilm, Z75%+J25% reduced 84.3% in 24 h. In conclusion association of glycolic extracts provided therapeutic effect, demonstrated antimicrobial activity and low cytotoxicity.

RESUMO JUSTIFICATIVA E OBJETIVOS: O objetivo deste estudo foi identificar a existência de relação entre o tipo de lócus de controle da saúde com as variáveis associadas à ocorrência de dor lombar crônica inespecífica (DLCI), além de avaliar a relação do nível de incapacidade no desenvolvimento de atividades funcionais e o nível de cinesiofobia com o tipo de lócus encontrado nos pacientes. MÉTODOS: Foram avaliados 40 indivíduos com idade média de 54,1±7,1 anos. Em uma única ocasião foram aplicados os questionários Multidimensional Scale of Locus of Health Control (MHLC), Tampa (cinesiofobia), e Roland-Morris (incapacidade) para a aquisição de variáveis qualitativas, analisadas para identificação de possíveis relações entre essas e o tipo de lócus de controle da saúde. RESULTADOS: Não houve correlação entre o tipo de lócus e as variáveis individuais específicas, tais como sexo (p<0,722), convênio de saúde (p<0,449), escolaridade (p<0,968), renda mensal (p<0,655), tabagismo (p<0,877), prática de atividade física (p<0,077) e estado civil (p<0,346), demonstrando homogeneidade da amostra. Não houve relação do tipo de lócus com o grau de cinesiofobia (p<0,745). Foi demonstrada relação significativa entre o lócus de controle interno e o nível de incapacidade (p<0,031). CONCLUSÃO: O tipo de lócus de controle da saúde apresentado pela maioria dos pacientes com DLCI foi o interno, relacionado a maiores níveis de incapacidade, e não associado aos níveis de cinesiofobia ou variáveis individuais.

ABSTRACT BACKGROUND AND OBJECTIVES: The aim of this study was to identify the existence of a relationship between the type of locus of health control and the variables associated with the occurrence of non-specific chronic low back pain (NCLBP), in addition to assessing the relationship between the level of disability in the development of functional activities and the level of kinesiophobia with the type of locus found in patients. METHODS: 40 individuals with a mean age of 54.1±7.1 years were evaluated. On a single occasion, the questionnaires Multidimensional Scale of Locus of Health Control (MSLHC), Tampa (kinesiophobia), and Roland-Morris (disability) were applied for the acquisition of qualitative variables, analyzed to identify possible relationships between these and the type of locus of health control. RESULTS: The present results showed no correlation between the type of locus and the specific individual variables genders (p<0.722), health insurance (p<0.449), education (p<0.968), monthly income (p<0.655), smoking (p<0.877), physical activity (p<0.077), and marital status (p<0.346), demonstrating homogeneity of the sample. There was no relationship between the type of locus and the degree of kinesiophobia (p<0.745). A significant relationship has been demonstrated between the locus of internal control and the level of disability (p<0.031). CONCLUSION: The type of locus of health control presented by most patients with NCLBP was the internal, related to higher levels of disability, and not associated with levels of kinesiophobia or individual variables.

Abstract Intraspecies or interspecies crossings transfer relevant alleles between plants. However, some interspecies crossings involving Passiflora species impede ovule fertilization and the viable development of seeds. Thus, the purpose of this study was to verify the viability of interspecific crossings and monitor pollen tube development. The experiment had six species of Passiflora in the reciprocal crossings. Histochemical tests aimed to evaluate the percentage of intraspecies or interspecies crossings that resulted in fruit development and pollen tube development. Ovule fertilization and fruit development occurred in determined directions of crossings when controlling the female or male genitor, but only one case of reciprocal crossing had success. In crossings with no fruit development, histological analysis showed that some callus developed in the stigma and style, confirming unilateral and interspecies incompatibility in the genus Passiflora to some species and some directions of crossings.

Resumo Introdução: A atribuição de um papel protetor da musculatura sobre as estruturas passivas da coluna vertebral faz com que sua estabilização e consequente manutenção tornem-se aspectos associados a dor, principalmente na região do complexo lombo-pélvico-quadril. Objetivo: Verificar a prevalência de dor e a associação da sua presença a déficits musculares em estudantes do ensino superior. Método: Estudo descritivo, observacional e transversal que avaliou 120 universitários através de questionários (caracterização da amostra, nórdico de sintomas osteomusculares, escala visual analógica de dor e internacional de atividade física). Foram executadas provas de resistência muscular do tronco (força muscular) e ponte com extensão unilateral do joelho (alinhamento pélvico). Resultados: Foi encontrada alta prevalência de dor na região lombar (58,41%). Não houve associação entre a presença de dor, força muscular e alinhamento pélvico (p > 0,05). Houve associação entre o teste de extensão de tronco e inclinação pélvica (p = 0,009). Conclusão: Foi identificada uma alta prevalência de dor lombar, baixo desempenho nas provas de resistência dos músculos do tronco e níveis de desalinhamento pélvico leve e moderado. Não houve associação entre as variáveis dor, fraqueza muscular do tronco e desalinhamento pélvico. Houve associação entre o desalinhamento pélvico e a fraqueza dos músculos extensores do tronco.

Abstract Introduction: The protective role of muscles in the passive structures of the spine means that their stability and consequent maintenance are associated with pain, especially in the region of the lumbo-pelvic-hip complex. Objective: To determine the prevalence of pain and its association with muscle deficits in higher education students. Method: Descriptive, observational, cross-sectional study that evaluated 120 university students through questionnaires (sample characterization, Nordic musculoskeletal symptoms, pain visual analogue scale and international physical activity). Trunk muscle strength and bridge tests with unilateral knee extension (pelvic alignment) were performed. Results: A high prevalence of pain was found in the lower back (58.41%). There was no association between the presence of pain, muscle strength and pelvic alignment (p> 0.05). There was an association between the trunk extension and pelvic tilt tests (p = 0.009). Conclusion: A high prevalence of low back pain, poor performance in the trunk muscle endurance tests and mild and moderate pelvic misalignment were identified. There was no association between pain, trunk muscle weakness and pelvic misalignment. There was an association between pelvic misalignment and trunk extensor muscle weakness.

Resumo A propagação seminífera de maracujá azedo (Passiflora edulis Sims) é o principal tipo de multiplicação devido à facilidade na formação de mudas. No entanto, o reduzido número de cultivares produtivas e homogêneas reflete a necessidade de melhoramento genético. O objetivo deste trabalho foi avaliar os efeitos maternos e recíprocos no vigor e na germinação de sementes de maracujá. O experimento foi conduzido em delineamento inteiramente casualizado, no esquema fatorial, com duas estruturas genéticas (híbrido e recíproco) e dez cruzamentos, com quatro repetições (50 sementes), em bandejas contendo areia inerte na câmara de germinação. Antes da semeadura, foi obtido o peso de 100 sementes, e aos 28 dias, foram avaliados a porcentagem de germinação, o índice de velocidade de emergência, comprimento total de plântulas, comprimento de parte aérea e raiz principal, número de plântulas normais e massa seca por plântulas. Os efeitos recíprocos dizem qual genótipo é mais promissor quando usado como genitor feminino ou masculino para a característica estudada. Pode-se inferir que há efeito materno influenciando o peso de 100 sementes, a emergência, o índice de velocidade de emergência e o número de mudas normais. Houve influência dos pais na expressão de caracteres em sementes de maracujá azedo. É importante definir os pais paterno e materno para obter sementes com alto potencial de germinação.

Abstract The seminiferous propagation of Sour Passion Fruit (Passiflora edulis Sims) is the main kind of multiplication due to the ease formation of seedlings. However, the reduced number of productive and homogeneous cultivars reflects the need for genetic breeding. The objective of this study was to assess the maternal and reciprocal effects in vigor and germination of Sour Passion Fruit seeds. The experiment was conducted in a completely randomized design in the factorial scheme, with two structure (hybrid and reciprocal) and ten crosses with four replicates (50 seeds) in trays containing inert sand in germination chamber. Before sowing, it was obtained the weight of 100 seeds, and at 28 days germination percentage, emergence speed index, total seedlings length, shoot length and main root length, number of normal seedlings and dry mass per seedlings were evaluated. The reciprocal effects tell us which genotype is most promising when used as the female or male parent for the trait studied. It can be inferred that there is maternal effect influencing the weight of 100 seeds, emergence, emergence speed index and the number of normal seedlings. There was influence of the parent on the expression of traits in seeds of Sour Passion Fruit. It is important to define the paternal and maternal parent to obtain seeds with high germination potential.

The essential oil of the leaves of Eugenia sulcata, in the Myrtaceae family, has a demonstrated antihypertensive effect, but its effects on heart muscle and its toxicity have not yet been elucidated. Little chemical or biological data are available for E. sulcata, whether emphasizing the beneficial effects or the pharmacological security of this species. This study aims to evaluate myocardial contractility and to analyze angiotensin converting enzyme (ACE) and myosin ATPase activities associated with use of this essential oil. In addition, we evaluated the immunotoxicity of E. sulcata essential oil. Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR) were treated daily for 30 days (10 mg/kg of oil) to evaluate the isometric force of the papillary muscle, ACE measured by fluorimetry, and myosin ATPase activities by inorganic phosphate. Lymphocyte cultures were used to evaluate cytotoxicity, DNA damage, and mutagenicity of the essential oil. The results demonstrate that the treatment did not change the cardiac contraction force and did not alter the functioning of the sarcoplasmic reticulum, extrusion of the membrane calcium, or modify the membrane calcium channels or β-adrenergic receptor activity. Tetanic contractions were potentiated in the SHR animals. Myosin ATPase activity was also increased in the SHR animals. Cardiac ACE activity was reduced in both animal strains, and the serum ACE was reduced only in the SHR animals. The essential oil did not cause cytotoxicity or mutagenicity and presented low DNA damage. Our results demonstrated that the essential oil does not change myocardial contractility and does not present relevant immunotoxicity.

ABSTRACT. The production of compact plants, which are slightly lacking in vigor and as productive as conventionally sized plants, is a trend in fruit growing. The objective of this study was to evaluate the vegetative performance and fruit quality of Gulfblaze and Reubennel plums intergrafted into two peach genotypes (UFV 186 and UFV 286). The experiment was arranged in a randomized block design using a 3x2 factorial arrangement (interstocks x cultivar) with four replications and one plant per plot. The non-intergrafted treatment was considered the control. Ten fruits were collected per plot for physical and chemical analyses. The evaluations were performed in the years 2014 and 2015. The interstock UFV 286 produced Gulfblaze trees with lower height in the two years of evaluation. When using the UFV 286 interstock, the trunk diameters were 50.2% smaller in Gulfblaze and 44.25% smaller in Reubennel than the control cultivars. Intergrafting had no influence on the fruit mass of Reubennel. In general, the peach genotypes UFV 186 and UFV 286 can be recommended as interstocks for reducing plant size in the plums studied. Intergrafting had no effect on fruit quality of Reubennel plums.

RESUMO Objetivo: Investigar a acurácia da ausculta torácica na detecção de mecânica respiratória anormal. Métodos: Foram avaliados 200 pacientes sob ventilação mecânica no pós-operatório imediato de cirurgia cardíaca. Foi avaliada a mecânica do sistema respiratório - complacência estática do sistema respiratório (Cest,sr) e resistência do sistema respiratório (R,sr) - e, em seguida, dois examinadores independentes, que desconheciam os dados referentes à mecânica do sistema respiratório, realizaram a ausculta torácica. Resultados: Nem murmúrio vesicular diminuído/abolido nem crepitações foram associados à Cest,sr reduzida (≤ 60 ml/cmH2O), independentemente do examinador. A acurácia global da ausculta torácica foi de 34,0% e 42,0% para os examinadores A e B, respectivamente. A sensibilidade e a especificidade da ausculta torácica para a detecção de murmúrio vesicular diminuído/abolido e/ou crepitações foi de 25,1% e 68,3%, respectivamente, para o examinador A, versus 36,4% e 63,4%, respectivamente, para o examinador B. Com base nos julgamentos feitos pelo examinador A, houve uma fraca associação entre R,sr aumentada (≥ 15 cmH2O/l/s) e roncos e/ou sibilos (ϕ = 0,31, p < 0,01). A acurácia global para a detecção de roncos e/ou sibilos foi de 89,5% e 85,0% para os examinadores A e B, respectivamente. A sensibilidade e a especificidade para a detecção de roncos e/ou sibilos foi de 30,0% e 96,1%, respectivamente, para o examinador A, versus 10,0% e 93,3%, respectivamente, para o examinador B. Conclusões: A ausculta torácica não parece ser um método diagnóstico acurado para a detecção de mecânica respiratória anormal em pacientes sob ventilação mecânica no pós-operatório imediato de cirurgia cardíaca.

ABSTRACT Objective: To investigate the accuracy of chest auscultation in detecting abnormal respiratory mechanics. Methods: We evaluated 200 mechanically ventilated patients in the immediate postoperative period after cardiac surgery. We assessed respiratory system mechanics - static compliance of the respiratory system (Cst,rs) and respiratory system resistance (R,rs) - after which two independent examiners, blinded to the respiratory system mechanics data, performed chest auscultation. Results: Neither decreased/abolished breath sounds nor crackles were associated with decreased Cst,rs (≤ 60 mL/cmH2O), regardless of the examiner. The overall accuracy of chest auscultation was 34.0% and 42.0% for examiners A and B, respectively. The sensitivity and specificity of chest auscultation for detecting decreased/abolished breath sounds or crackles were 25.1% and 68.3%, respectively, for examiner A, versus 36.4% and 63.4%, respectively, for examiner B. Based on the judgments made by examiner A, there was a weak association between increased R,rs (≥ 15 cmH2O/L/s) and rhonchi or wheezing (ϕ = 0.31, p < 0.01). The overall accuracy for detecting rhonchi or wheezing was 89.5% and 85.0% for examiners A and B, respectively. The sensitivity and specificity for detecting rhonchi or wheezing were 30.0% and 96.1%, respectively, for examiner A, versus 10.0% and 93.3%, respectively, for examiner B. Conclusions: Chest auscultation does not appear to be an accurate diagnostic method for detecting abnormal respiratory mechanics in mechanically ventilated patients in the immediate postoperative period after cardiac surgery.